Josbert M Metselaar Selected Research

prednisolone phosphate

1/2022	Liposomal drug delivery system for anti-inflammatory treatment after cataract surgery: a phase I/II clinical trial.
1/2018	Evaluation of subconjunctival liposomal steroids for the treatment of experimental uveitis.
1/2017	Liposomal Treatment of Experimental Arthritis Can Be Monitored Noninvasively with a Radiolabeled Anti-Fibroblast Activation Protein Antibody.
7/2008	Liposomal glucocorticoids as tumor-targeted anti-angiogenic nanomedicine in B16 melanoma-bearing mice.
2/2008	Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue.
6/2006	Anti-angiogenic effects of liposomal prednisolone phosphate on B16 melanoma in mice.
2/2005	Liposome-encapsulated prednisolone phosphate inhibits growth of established tumors in mice.
11/2003	A novel family of L-amino acid-based biodegradable polymer-lipid conjugates for the development of long-circulating liposomes with effective drug-targeting capacity.
7/2003	Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes.

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Josbert M Metselaar Research Topics

Disease

19	Neoplasms (Cancer) 04/2022 - 02/2005
18	Inflammation (Inflammations) 01/2022 - 07/2003
7	Arthritis (Polyarthritis) 01/2018 - 01/2002
6	Atherosclerosis 09/2017 - 12/2010
5	Rheumatoid Arthritis 01/2022 - 01/2006
5	Hypersensitivity (Allergy) 01/2022 - 05/2013
5	Experimental Arthritis 01/2018 - 07/2003
4	Prostatic Neoplasms (Prostate Cancer) 10/2021 - 05/2014
4	Atherosclerotic Plaque (Atheroma) 01/2016 - 12/2010
4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 10/2011 - 08/2003
4	Multiple Sclerosis 10/2011 - 08/2003
3	Multiple Myeloma 10/2020 - 01/2019
2	Reperfusion Injury 01/2022 - 01/2018
2	Neoplasm Metastasis (Metastasis) 01/2021 - 06/2015
2	Pulmonary Hypertension 10/2019 - 12/2014
2	Carcinoma (Carcinomatosis) 05/2014 - 02/2005
2	Experimental Melanoma 07/2008 - 06/2006
1	Hypoxia (Hypoxemia) 01/2022
1	Ischemia 01/2022
1	Cataract (Cataracts) 01/2022
1	Psoriasis (Pustulosis Palmaris et Plantaris) 07/2021
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2021
1	Stomach Neoplasms (Stomach Cancer) 01/2021
1	Fistula 08/2020
1	COVID-19 01/2020
1	Hematologic Neoplasms (Hematological Malignancy) 01/2019
1	Adenocarcinoma 01/2019
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019
1	Kidney Diseases (Kidney Disease) 01/2018
1	Uveitis 01/2018
1	Myocardial Infarction 10/2017
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2017
1	Breast Neoplasms (Breast Cancer) 01/2016
1	Hyperplasia 01/2016
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2016
1	Arteriovenous Fistula 01/2016

Drug/Important Bio-Agent (IBA)

31	Liposomes (Liposome)IBA 01/2022 - 01/2002
14	Prednisolone (Predate)FDA LinkGeneric 01/2022 - 08/2003
14	Pharmaceutical PreparationsIBA 06/2020 - 02/2005
14	GlucocorticoidsIBA 01/2019 - 01/2002
9	prednisolone phosphate FDA LinkGeneric 01/2022 - 07/2003
5	Dexamethasone (Maxidex)FDA LinkGeneric 10/2021 - 01/2014
4	Proteins (Proteins, Gene)FDA Link 01/2018 - 12/2010
3	SteroidsIBA 01/2022 - 01/2018
3	MicellesIBA 01/2021 - 01/2014
3	PolymersIBA 06/2020 - 11/2003
3	Therapeutic UsesIBA 01/2018 - 10/2011
3	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 09/2003 - 07/2003
2	ProdrugsIBA 01/2022 - 01/2014
2	Methylprednisolone FDA LinkGeneric 01/2022 - 06/2008
2	Ophthalmic Solutions (Eye Drops)IBA 01/2022 - 12/2021
2	Docetaxel (Taxotere)FDA Link 01/2021 - 01/2016
2	Bortezomib (Velcade)FDA Link 10/2020 - 12/2019
2	Phosphates (Orthophosphate)IBA 01/2018 - 09/2011
2	AntigensIBA 01/2018 - 07/2015
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 09/2017 - 12/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2003 - 08/2003
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 04/2022
1	Carboplatin (JM8)FDA LinkGeneric 04/2022
1	Cisplatin (Platino)FDA LinkGeneric 04/2022
1	Coordination ComplexesIBA 04/2022
1	QuercetinIBA 01/2022
1	DEPOIBA 01/2022
1	GlucuronidaseIBA 01/2022
1	EnzymesIBA 01/2022
1	Immunomodulating AgentsIBA 01/2021
1	Proteasome InhibitorsIBA 12/2019
1	Thromboxane B2IBA 10/2019
1	Gemcitabine FDA Link 01/2019
1	dexamethasone 21-phosphate FDA LinkGeneric 01/2019
1	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 01/2018
1	Interleukin-22 (IL-22)IBA 01/2018
1	BerberineIBA 10/2017
1	Biological ProductsIBA 09/2017
1	Apolipoproteins E (ApoE)IBA 09/2017
1	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 09/2017
1	HDL LipoproteinsIBA 09/2017
1	Simvastatin (Zocor)FDA LinkGeneric 09/2017
1	ApolipoproteinsIBA 09/2017
1	AsparagineIBA 01/2017
1	Asparaginase (Elspar)FDA Link 01/2017
1	LipidsIBA 01/2016
1	Fish OilsIBA 01/2016
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2016
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2016
1	Docosahexaenoic AcidsIBA 01/2016
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2016
1	N 30IBA 07/2015
1	Drug CarriersIBA 06/2015
1	Complement System Proteins (Complement)IBA 12/2014

Therapy/Procedure

15	Therapeutics 04/2022 - 07/2003
5	Intravenous Administration 10/2019 - 07/2003
3	Drug Therapy (Chemotherapy) 01/2021 - 05/2014
2	Castration 10/2021 - 05/2014
2	Aftercare (After-Treatment) 01/2017 - 07/2003
1	Immunotherapy 04/2022
1	Lasers (Laser) 01/2022
1	Transplantation 07/2021
1	Decompression 01/2019
1	Renal Dialysis (Hemodialysis) 01/2016